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2022, Vol. 26 ›› Issue (22): 3505-3513Cell co-culture and in vivo biocompatibility of poly(L-lactic caprolactone)/silk fibroin small-diameter artificial blood vesselsLiu Yue1, Jiang Ziyi1, Li Jingjing2,3, Meng Kai1, Zhao Huijing1
Abstract: BACKGROUND: The autologous bypass grafting is the best surgical scheme. However, the source of autologous blood vessels is limited, which is far from meeting the huge clinical needs. Therefore, the research and development of small-diameter artificial blood vessels are of great significance. However, small-diameter artificial blood vessels have not been truly applied in clinical practice due to the problems of easy thrombosis and intimal hyperplasia. |