2022, Vol. 26 ›› Issue (27): 4401-4405

Influencing factors and precautions of new vertebral fractures after vertebroplasty for osteoporotic vertebral fractures

Wang Qian1, Dong Junfeng1, 2   

Abstract: BACKGROUND: Vertebroplasty has been widely used in the clinical treatment of osteoporotic vertebral compression fractures, but postoperative vertebral fractures are easy to occur, which reduces the overall efficacy.
OBJECTIVE: To analyze the influencing factors and precautions of new fracture after vertebroplasty for osteoporotic vertebral compression fracture, so as to guide clinical diagnosis and treatment and prevent new fracture after surgery, which is a common complication.
METHODS: The first author searched PubMed, CNKI, Wanfang, and VIP databases for new vertebral fractures after vertebroplasty for osteoporotic vertebral compression fractures from 2006 to 2021. The search terms were “osteoporotic vertebral compression fractures, vertebroplasty, new vertebral fractures” in Chinese and English. The authors excluded the articles with low relevance, outdated research content and repeatability, and then made a review.
RESULTS AND CONCLUSION: The factors that affect new vertebral fractures after vertebroplasty are divided into two categories based on whether they are related to surgery: (1) the patient’s own factors, including age, gender, body mass index, osteoporosis, glucocorticoid use, and mental factors. (2) Factors related to vertebroplasty include kyphosis angle, number of vertebra, intraoperative height of vertebra recovery, cement injection volume, and bone cement extravasation. There are many influencing factors, and the comprehensive findings are mainly divided into osteoporosis, changes in vertebral pressure and changes in vertebral range of motion. It is necessary to carry out targeted prevention and treatment from these three aspects to reduce the incidence of new postoperative fractures and improve the prognosis of patients. The next research direction will be to improve the surgical method and find the bone cement with more suitable strength, better biocompatibility and more convenient filling.
Key words: bone cement, osteoporosis, vertebral compression fracture, vertebroplasty, new vertebral fractures, influencing factor, review