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2022, Vol. 26 ›› Issue (4): 610-616Application and value of polymer materials in three-dimensional printing biological bones and scaffoldsWang Ruanbin1, Cheng Liqian1, Chen Kai2
Abstract: BACKGROUND: At present, the main factors restricting the development of three-dimensional (3D) technology are the limited types of printable materials, and polymer materials have made great progress in the field of 3D printing biological bones and scaffolds due to their excellent physical and chemical properties and variety. OBJECTIVE: To review application status of polymer materials in the biological field and the advantages and disadvantages of 3D printing technology. METHODS: CNKI, Wanfang, VIP, and PubMed databases were searched for articles published from 2000 to 2020. The Chinese key words were “3D printing, fused deposition molding, UV curing molding technology, selective laser sintering technology, natural polymer, synthetic polymer, biomedical, artificial bone, artificial bone scaffold”. The English key words were “3D printing; FDM; SLA; SLS; natural polymer; synthetic polymer; biomedical; artificial bone; artificial bone scaffold”. Finally, 56 articles were selected to summarize. RESULTS AND CONCLUSION: Polymer materials play a more and more important role in the biological field because of their wide variety, excellent physical and chemical properties, high dimensional accuracy, good processability and other characteristics. Not only that, the composite of polymer materials with metal and inorganic can improve their biocompatibility, controllable degradation and other characteristics, which further expands the application space of polymer materials in the biological field. 3D printing technology is mainly through the combination of information technology and manufacturing technology to achieve 3D solid printing, which is with the characteristics of rapid, accurate, personalized customization. 3D printing is widely used in biomedical, casting, aerospace and other fields. The combination of polymer materials and 3D printing technology can realize the personalized customization of human bones, organs and tissues, which is expected to solve the problem of insufficient donors in clinic. Therefore, the research and development of biomedical materials more suitable for 3D printing process and how to better combine polymer materials with 3D printing technology become the current research hotspot. Key words:3D printing, polymer materials, biomedicine, bone, bone scaffold, review |