Journal Info

Journal Info

副标题

For Authors

For Authors

副标题

For Reviewers

For Reviewers

副标题

2022, Vol. 26 ›› Issue (7): 1130-1136

Potential of muscle-derived stem cells in peripheral nerve regeneration

An Weizheng, He Xiao, Ren Shuai, Liu Jianyu   

  1. First Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China

  • Received:2020-12-23 Revised:2020-12-25 Accepted:2021-02-22 Online:2022-03-08 Published:2021-10-29

  • Contact: Liu Jianyu, MD, Chief physician, Professor, First Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China

  • About author:An Weizheng, Master candidate, First Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin 150000, Heilongjiang Province, China

  • Supported by:

    the National Natural Science Foundation of China, No. 81971828 (to LJY)



Abstract: BACKGROUND: Muscle-derived stem cells have strong self-renewal and multi-directional differentiation potential, which has a wide application prospect in the field of nerve injury repair.
OBJECTIVE: To review the treatment status of peripheral nerve injury and research progress of muscle-derived stem cells in the treatment of peripheral nerve injury.
METHODS: “Muscle-derived stem cell, peripheral nerve injury, tissue engineering, Schwann cell, transplant, regeneration, nerve conduit” were the search words. The articles in PubMed, CNKI and Wanfang databases were cross-searched. After excluding repetitive research and irrelevant articles, 100 articles were finally included for review.  

RESULTS AND CONCLUSION: Muscle-derived stem cells show good regenerative potential in repairing nerve injury by differentiating into various kinds of support cells needed for nerve regeneration and powerful secretory function.

Key words:muscle-derived stem cells, peripheral nerve injury, Schwann cells, transplantation, nerve conduit, regeneration, neurotrophic factor, tissue engineering, differentiation, review


分享到:

Publishing Information

Publishing House of Chinese Journal of Tissue Engineering Research


The Official Publication of

Chinese Association of Rehabilitation Medicine

Contact Us

General editorial enquiries:

Email: bwb01@crter.org

Copyright related contact:

Email: crter@crter.org

Commercial Sales contact (Reprints, advertising, etc.):

Email: bwb@crter.org