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2023, Vol. 27 ›› Issue (12): 1884-1891Curcumin loaded injectable microspheres retard progression of intervertebral disc degenerationYe Xuwen, Gu Yong, Chen Liang
Abstract: BACKGROUND: The mechanism of intervertebral disc degeneration is complicated. The activation of inflammatory pathways, the proliferation of inflammatory factors, and the excessive accumulation of reactive oxygen species can all accelerate the process of intervertebral disc degeneration. Curcumin is a natural drug extracted from traditional Chinese medicine curcuma, which has pharmacological effects such as inhibiting inflammation, antioxidant stress and so on. |