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2023, Vol. 27 ›› Issue (19): 2980-2985Effect of the frequency of bone marrow mesenchymal stem cell infusion on pulmonary fibrosis in silicosis ratsZhang Ying, Huang Ming, Lu Fengrong, Cai Tingfeng, Li Ruiwen
Abstract: BACKGROUND: Preliminary studies of the research team have shown that bone marrow mesenchymal stem cells can reduce pulmonary inflammation and pulmonary fibrosis in rats caused by silica dust, and no obvious rejection or side effects were found. However so far, almost all reports on the treatment of silicosis animals with bone marrow mesenchymal stem cells are single infusion, and there is no report comparing the effect of multiple repeated infusions and single infusions. Key words: mesenchymal stem cell, silicosis, rat, pulmonary fibrosis, infusion frequency, cell transplantation |