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2023, Vol. 27 ›› Issue (19): 3052-3060Recent advances of engineered exosomes and challenges on clinical translational researchZhang Qi, Yu Mei, Liu Lei, Tian Weidong
Abstract: BACKGROUND: Currently, exosomes were widely attracted as a new form of drug carrier by many researchers. Based on the modification by different bioengineering techniques, natural exosomes were engineered to obtain the enhanced exosomal characteristics and functions. Key words: exosome, bioengineering, engineered exosome, clinical translation, scale production, isolation and purification, ingredient characterization, quality control, storage stability, product safety |