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2023, Vol. 27 ›› Issue (20): 3129-3135Icariin promotes osteoblast proliferation and differentiation through a non-nuclear signaling pathwayMei Jie1, 2, He Qiang1, 3, Sun Xin1, Yin Hong1, Qian Weiqing1
Abstract: BACKGROUND: Estrogen deficiency can inhibit osteoclast proliferation and differentiation. Epimedium is a phytoestrogen that acts as a traditional kidney tonic herb, and its active ingredient, icariin, can produce some effects of estrogen. Key words: icariin, osteoblast, proliferation, differentiation, non-nuclear effect, signaling pathway |