|
2023, Vol. 27 ›› Issue (20): 3158-3166Effects of Santong electroacupuncture on the activity of cytoplasmic phospholipase A2 in rats with spinal cord injury via the Rho/Rho kinase and MEK/ERK signaling pathwaysYao Haihua1, Min Youjiang1, 2, Hong Dongying3, Wang Li2, Lu Xiuyun2, Yang Yihua2
Abstract: BACKGROUND: Cytoplasmic phospholipase A2 (cPLA2) is a novel strategy and target for the treatment of spinal cord injury. cPLA2 is regulated by RhoA/Rho kinase and mitogen-activated protein kinase (MEK)/extracellular regulated protein kinases (ERK) signaling pathways. Electroacupuncture can treat spinal cord injury by regulating the RhoA/Rho kinase and MEK/ERK signaling pathways. Key words: electroacupuncture, spinal cord injury, Rho/Rho kinase signaling pathway, MEK/ERK signaling pathway, cytoplasmic phospholipase A2 |