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2023, Vol. 27 ›› Issue (26): 4161-4167Effects of sodium arsenite on human umbilical vein endothelial cell injury and sphingosine kinases 1/sphingosine 1-phosphate signaling axisFang Xingyan1, Tian Zhenli1, Zhao Zheyi2, Wen Ping3, Xie Tingting1
Abstract: BACKGROUND: Vascular endothelial cells are the main target of arsenic toxicity and the molecular mechanism of arsenic-induced endothelial cell injury needs to be further studied. Key words: sodium arsenite, human umbilical vein endothelial cell, oxidative stress, apoptosis, inflammation, sphingosine kinase 1/sphingosine 1-phosphate signaling axis |