|
2023, Vol. 27 ›› Issue (31): 5028-5034Effect of Illicium henryi extract on angiogenesis in rats with osteoporotic fracturesShi Guirong1, Ren Bowen2, Zhang Zhongbo2, Wang Lisha2, Zhang Qiwei2, Shi Dongliang2
Abstract: BACKGROUND: The extract of Illicium henryi is a Chinese herbal preparation with anti-inflammatory and analgesic properties and invigorating blood circulation and stasis. Its ethanol extract has markedly curative effect on rat soft tissue injury. However, there is yet no report on whether Illicium henryi has therapeutic effect on osteoporotic fractures. Key words: Illicium henryi, osteoporosis, fracture, human microvascular endothelial cell, NRF1, the PI3K/AKT pathway |