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2023, Vol. 27 ›› Issue (31): 5078-5084Research and advance in intervertebral disc annulus fibrosus repairLiu Xin1, 2, Sun Tianze1, 2, Zhang Jing1, 2, Zhang Wentao1, 2, Li Zhonghai1, 2
Abstract: BACKGROUND: Lumbar intervertebral disc herniation is a common clinical disease. Its incidence is increasing year by year, which seriously affects the quality of life of patients and brings huge economic losses to the families of patients and society. At present, it is considered that the destruction of the integrity of intervertebral disc fibrous annulus is an important factor affecting the occurrence and development of lumbar disc herniation. Therefore, it is of great significance to restore the integrity of the annulus fibrosus for the treatment and prevention of lumbar disc herniation. Key words: annulus fibrosus, intervertebral disc, tissue engineering, biotherapy, hyaluronic acid, radiofrequency thermocoagulation technology, repair, regeneration |