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2024, Vol. 28 ›› Issue (23): 3736-3742Osteoprotegerin/receptor activator of nuclear factor kappa-B/receptor activator of nuclear factor kappa-B ligand and the application of relevant target therapy in oral medicineZhou Jing, Zhang Zhao
Abstract: BACKGROUND: Osteoprotegerin (OPG)/receptor activator of nuclear factor-κB (RANK)/receptor activator of nuclear factor-κB ligand (RANKL) are important cytokines for coupling osteoclast and osteoblast differentiation and activation, and are key factors for regulating bone metabolism, which affect the immune system, bone regeneration and remodeling, and are closely related to the physiological and pathological remodeling of the alveolar bone. Key words: anti-receptor activator of nuclear factor-κB ligand, osteoprotegerin, anti-receptor activator of nuclear factor-κB ligand antibody, receptor activator of nuclear factor-κB ligand, alveolar bone resorption |