2025, Vol. 29 ›› Issue (34): 7461-7469

Patent technology analysis of platelet-rich plasma preparation devices

Que Meng1, 2, Gao Fengqing1, 2, He Yang3, Ruan Changgeng3   

Abstract: BACKGROUND: Platelet-rich plasma is an important material for tissue repair and is widely used in orthopedics, wound repair, plastic surgery and other fields. The device for preparing platelet-rich plasma has become a hot spot in the field of patent applications.
OBJECTIVE: To analyze the trend of patent applications for platelet-rich plasma separation devices at home and abroad.
METHODS: Using the patent retrieval system of China National Intellectual Property Administration, Patsnap and Himpat patent databases, we searched the patent literature of platelet-rich plasma separation devices, and analyzed the patent application trend of platelet-rich plasma separation devices from the aspects of patent application volume, licensing rate, technical theme, typical applicant patent layout, etc. The patent retrieval system of China National Intellectual Property Administration was developed by the China National Intellectual Property Administration and includes patent data from 103 countries, regions and organizations. The Patsnap patent database was developed by PatSnap, Singapore and has 120 million patent data from more than 100 countries, providing multi-language translation and multi-language search. The Himpat patent database was developed by Himpat, China and includes more than 160 million patents from 123 countries/organizations/regions around the world since 1800, and is translated into high-fidelity Chinese and English versions, and is updated twice a week.
RESULTS AND CONCLUSION: The patent application for platelet-rich plasma separation devices in China started about 10 years later than abroad, and the number of patent applications in China has sharply increased since 2017. The trend of patent applications abroad is relatively stable. Most domestic and foreign patent applications are in the stage of authorization and maintenance, with enterprises being the main applicants. The classification of platelet-rich plasma devices on the market is very confusing. In this study, they are divided into nine subcategories based on device structure. Chinese patent applications mainly focus on separation cylinder devices, while foreign applications focus on automated separation devices. China should be market-oriented and technology oriented, develop innovative platelet-rich plasma devices, lay out global patent layouts, and promote the development of China’s medical device industry.

Key words: platelet-rich plasma preparation device, platelet-rich plasma, patent layout, patent technology, engineered material