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2025, Vol. 29 ›› Issue (36): 7719-7727Comparison of osteogenic potential in STRO-1 positive and negative bone marrow mesenchymal stem cellsZhou Wanlin1, He Bin2, Shen Xiongcheng1, Huang Kun1, Tian Renyuan1, Yuan Ye1, Huang Wenliang3
Abstract: BACKGROUND: With aging, the regenerative capacity and differentiation function of bone marrow mesenchymal stem cells progressively decline, reducing bone tissue repair efficacy. Thus, identifying bone marrow mesenchymal stem cell subpopulations with enhanced osteogenic potential is of significant importance for advancing bone tissue engineering. Key words: STRO1, bone marrow mesenchymal stem cells, osteogenic differentiation, immunomagnetic cell sorting, bone defect repair, seed cells, bone tissue engineering, engineered stem cells |